APPENDIX 2.

OR for attaining sustained remission.

VariableDAS28 Remission, OR (95% CI), pACR Excluding Laboratory, OR (95% CI), pACR Remission, OR (95% CI), pCDAI Remission, OR (95% CI), pSDAI Remission no final, initial used, OR (95% CI), p
Males0.84 (0.46–1.50), 0.5491.32 (0.56–3.12), 0.529not in modelnot in model0.45 (0.14–1.46), 0.185
RF +0.93 (0.49–1.74), 0.8141.25 (0.47–3.33), 0.659not in model0.51 (0.23–1.15), 0.1050.68 (0.20–2.32), 0.538
Baseline HAQ1.24 (0.76–2.03), 0.3910.74 (0.33–1.65), 0.456not in modelnot in model0.83 (0.29–2.57), 0.748
Disease duration (continuous)0.98 (0.96–1.01), 0.2760.98 (0.94–1.03), 0.425not in modelnot in model1.00 (0.94–1.06), 0.894
BMI ≥ 30not in model0.30 (0.10–0.90), 0.032not in modelnot in model0.42 (0.10–1.68), 0.218
Ex-/never smokernot in model3.28 (0.78–13.86), 0.107not in model2.11 (0.66–6.79), 0.2111.67 (0.26–10.78), 0.588
Blacknot in modelnot in modelnot in modelnot in modelnot in model
Aboriginalnot in modelnot in modelnot in modelnot in model1.08 (0.18–6.45), 0.937
Hispanicnot in modelnot in modelnot in modelnot in modelnot in model
East Indiannot in modelnot in modelnot in modelnot in modelnot in model
Asiannot in modelnot in modelnot in modelnot in modelnot in model
Separated/divorced/ widowed2.61 (0.85–7.95), 0.093not in model8.94 (0.79–101.5), 0.0771.78 (0.72–4.38), 0.2120.58 (0.07–4.70), 0.609
Married/common law2.52 (0.94–6.71), 0.065not in model4.29 (0.49–37.10), 0.186not in model0.63 (0.11–3.66), 0.607
High schoolnot in modelnot in modelnot in modelnot in model0.71 (0.11–4.77), 0.724
University/collegenot in modelnot in model2.09 (0.80–5.44), 0.133not in model0.74 (0.11–5.19), 0.764
Baseline disease activity scorenot in modelnot in modelnot in modelnot in modelnot in model
Baseline physician global0.80 (0.66–0.99), 0.0360.96 (0.67–1.38), 0.835not in modelnot in model1.34 (0.78–2.30), 0.289
Baseline patient globalnot in model1.07 (0.84–1.37), 0.582not in modelnot in model1.00 (0.71–1.39), 0.985
Baseline ESRnot in model1.00 (0.98–1.02), 0.984not in modelnot in model1.01 (0.99–1.04), 0.345
Baseline CRPnot in model1.06 (0.88–1.26), 0.5501.15 (0.98–1.36), 0.083not in model0.83 (0.61–1.12), 0.217
Total tender jointsnot in model0.98 (0.91–1.04), 0.448not in model0.96 (0.92–1.00), 0.0510.94 (0.86–1.03), 0.165
Total swollen jointsnot in model0.93 (0.84–1.03), 0.170not in modelnot in model0.94 (0.81–1.10), 0.450
Constant1.29 (0.28–5.93), 0.7430.55 (0.05–5.64), 0.6150.04 (0.00–0.40), 0.0060.59 (0.15–2.36), 0.4530.54 (0.01–36.30), 0.773
Goodness of fit (best close to 1)0.37640.23220.34340.61940.9957
Classification test65.22%73.20%77.06%70.81%78.76%
  • DAS28: Disease Activity Score (28 joints); HAQ: Health Assessment Questionnaire; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; CDAI: Clinical Disease Activity Index; SDAI: Simplified Disease Activity Index; RF: rheumatoid factor; ACR: American College of Rheumatology; BMI: body mass index.