Mean change in functional performance measures and muscle power variables*.
| Outcome | Change | ||||
|---|---|---|---|---|---|
| EX + EP | EP | Difference Between Means | 95% CI of Difference Between Means | p | |
| Functional performance | |||||
| Chair stands, s† | |||||
| All patients | −2.9 ± 0.4 | −0.9 ± 0.4 | 1.9 | 0.9;3.0 | 0.0003 |
| Knee OA | −3.0 ± 0.5 | −1.1 ± 0.5 | 1.9 | 0.5;3.3 | 0.0093 |
| Hip OA | −2.7 ± 0.5 | −0.8 ± 0.5 | 1.9 | 0.5;3.4 | 0.0106 |
| 20-m self-chosen pace, s† | |||||
| All patients | −1.2 ± 0.3 | −0.3 ± 0.3 | 0.9 | 0.0;1.8 | 0.0491 |
| Knee OA | −1.3 ± 0.4 | −0.9 ± 0.5 | 0.4 | −0.8;1.7 | 0.5100 |
| Hip OA | −1.1 ± 0.4 | 0.2 ± 0.5 | 1.4 | 0.1;2.7 | 0.0339 |
| 20 m maximal pace, s† | |||||
| All patients | 0.7 ± 0.3 | 0.1 ± 0.3 | 0.9 | −0.1;1.8 | 0.0645 |
| Knee OA | −0.5 ± 0.5 − | −0.4 ± 0.5 | 0.1 | −1.2;1.4 | 0.8648 |
| Hip OA | −1.0 ± 0.5 | 0.7 ± 0.5 | 1.6 | 0.3;3.0 | 0.0154 |
| Knee bends, no. Index† | |||||
| All patients | 3.3 ± 0.8 | −0.3 ± 0.8 | −3.6 | −5.8;−1.4 | 0.0018 |
| Knee OA | 2.2 ± 1.1 | −2.0 ± 1.3 | −4.1 | −7.3;−1.0 | 0.0115 |
| Hip OA | 4.3 ± 1.1 | 1.3 ± 1.2 | −3.0 | −6.2;0.1 | 0.0577 |
| Knee bends, no. Contra† | |||||
| All patients | 2.0 ± 0.8 | 0.5 ± 0.9 | −1.5 | −3.9;1.0 | 0.2349 |
| Knee OA | 0.7 ± 1.2 | −0.1 ± 1.3 | −0.8 | −4.3;2.7 | 0.6514 |
| Hip OA | 3.2 ± 1.2 | 1.1 ± 1.3 | −2.1 | −5.6;1.3 | 0.2185 |
| Leg muscle power | |||||
| Single-joint knee extension, W Index† | |||||
| All patients | 7.1 ± 3.3 | 4.5 ± 3.5 | −2.6 | −12.2;7.1 | 0.5970 |
| Knee OA | 9.3 ± 4.9 | −2.2 ± 5.1 | −11.6 | −25.6;2.5 | 0.1052 |
| Hip OA | 4.8 ± 4.6 | 11.2 ± 4.9 | 6.4 | −6.9;19.7 | 0.3424 |
| Single-joint knee extension, W Contra† | |||||
| All patients | 2.8 ± 2.8 | −0.7 ± 2.9 | −3.4 | −11.4;4.5 | 0.3935 |
| Knee OA | −2.2 ± 4.0 | −0.2 ± 4.1 | 2.0 | −9.2;13.3 | 0.7249 |
| Hip OA | 7.8 ± 3.9 | −1.1 ± 4.1 | −8.9 | −20.2;2.4 | 0.1206 |
| Single-joint hip extension, W Index† | |||||
| All patients | 2.6 ± 3.1 | −4.4 ± 3.2 | −7.0 | −15.9;1.9 | 0.1200 |
| Knee OA | 7.4 ± 4.2 | 1.3 ± 4.6 | −6.1 | −18.4;6.3 | 0.3315 |
| Hip OA | −2.1 ± 4.5 | −10.1 ± 4.6 | −7.9 | −20.7;4.8 | 0.2196 |
| Single-joint hip extension, W Contra† | |||||
| All patients | 10.6 ± 4.6 | 4.6 ± 4.8 | −6.0 | −19.2;7.3 | 0.3724 |
| Knee OA | 5.7 ± 6.5 | 11.5 ± 6.9 | 5.8 | −12.9;24.5 | 0.5420 |
| Hip OA | 15.5 ± 6.6 | −2.3 ± 6.8 | −17.8 | −36.5;0.9 | 0.0626 |
| Single-joint hip abduction, W Index† | |||||
| All patients | 5.4 ± 1.3 | 1.5 ± 1.4 | −3.9 | −7.8;−0.1 | 0.0448 |
| Knee OA | 5.0 ± 1.7 | 1.2 ± 1.9 | −3.9 | −9.0;1.2 | 0.1351 |
| Hip OA | 5.8 ± 2.0 | 1.9 ± 2.0 | −3.9 | −9.4;1.7 | 0.1701 |
| Single joint hip abduction, W Contra † | |||||
| All patients | 4.3 ± 2.4 | 4.4 ± 2.5 | 0.1 | −6.9;7.1 | 0.9814 |
| Knee OA | 4.8 ± 3.4 | 6.0 ± 3.6 | 1.2 | −8.6;11.1 | 0.8061 |
| Hip OA | 3.9 ± 3.5 | 2.8 ± 3.6 | −1.1 | −11.0;8.9 | 0.8342 |
| Multijoint leg extension, W Index† | |||||
| All patients | 6.5 ± 3.1 | 0.7 ± 3.2 | −5.9 | −14.6;2.9 | 0.1874 |
| Knee OA | 7.7 ± 4.3 | 2.7 ± 4.5 | −5.0 | −17.3;7.2 | 0.4167 |
| Hip OA | 5.4 ± 4.3 | −1.3 ± 4.6 | −6.7 | −19.1;5.8 | 0.2913 |
| Multijoint leg extension, W Contra† | |||||
| All patients | 12.1 ± 3.2 | 2.0 ± 3.4 | −10.1 | −19.3; −0.8 | 0.0328 |
| Knee OA | 5.6 ± 4.6 | −1.9 ± 4.7 | −7.5 | −20.5;5.4 | 0.2533 |
| Hip OA | 18.5 ± 4.6 | 5.8 ± 4.8 | −12.7 | −25.8;0.5 | 0.0592 |
↵* Values are mean ± SEM.
↵† Statistical analysis by analysis of covariance, adjusted for the effect of OA location and body mass index. EX + EP: 8 weeks exercise intervention plus educational package; EP: educational package alone; Index: leg to undergo surgery: Contra: contralateral leg; OA: osteoarthritis.