Table 3.

Body composition changes in patients with SpA receiving anti-TNF treatment over 6 months, 1 year, and 2 years.

	Change from Baseline to 6 mos	Change from 6 to 12 mos	Change from 6 to 24 mos	Change from Baseline to 1 yr	Change from Baseline to 2 yrs
Body weight, kg	0.7 ± 1.2	0.2 ± 1.1	0.1 ± 1.2	0.8 ± 1.4	0.9 ± 1.7
BMI, kg/cm²	0.5 ± 1.1^*	0.4 ± 1.0^*	0.1 ± 1.4	0.9 ± 1.4^**	0.7 ± 1.8^*
Fat mass	0.3 ± 0.6^*	0.3 ± 0.7^*	0.3 ± 0.8^*	0.6 ± 0.8^**	0.7 ± 1.0^**
Lean mass	0.4 ± 0.8^*	−0.1 ± 0.6	−0.2 ± 0.6	0.2 ± 0.8	0.2 ± 0.8
WC (cm)	2.2 ± 3.4^**	1.2 ± 2.7^*	1.0 ± 4.6	2.9 ± 4.4^**	4.1 ± 5.9^**
VAT area, cm²	13.7 ± 20.6^**	8.3 ± 17.5^*	11.2 ± 27.0^*	21.0 ± 26.6^**	29.1 ± 33.4^**
SAT area, cm²	12.5 ± 27.4^*	14.1 ± 24.9^*	14.2 ± 40.4^*	27.1 ± 38.2^**	1.9 ± 53.2^**
VAT/SAT	0.03 ± 0.06^*	0.00 ± 0.04	0.01 ± 0.06	0.02 ± 0.06^*	0.03 ± 0.06^*

↵* p < 0.05 ;
↵** p < 0.001. WC: waist circumference; BMI: body mass index; VAT: visceral adipose tissue; SAT: subcutaneous adipose tissue; SpA: spondyloarthritis; TNF: tumor necrosis factor.