Clinical and laboratory findings for group A.
| Case | Age, yrs | Sex | ANCA (EU) | Diagnosis | CRP, mg/dl | Cr, mg/dl | Hematuria, grade | Proteinuria g/day | Crescents (%) | Global Sclerosis (%) | Vasculitis | Organ Involvement (extrarenal) | Initial Therapy | Maintenance Therapy | Disease Duration (mos) | Relapse | End of Followup |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 71 | F | MPO 889 | MPA | 5.3 | 2.6 | 5 | 1.03 | 28 | 0 | Interlobular | ILD | PSL CYC | PSL | 35 | 1 | Cr 1.0 |
| 2 | 84 | F | MPO 297 | MPA | 2.7 | 8.7 | 4 | 1.62 | 67 | 0 | Interlobular | (–) | PSL CYC | 2 | 0 | Death (renal failure) | |
| 3 | 60 | F | MPO 640 | MPA | 8.79 | 1.12 | 5 | 0.0 | 42 | 11 | Arteriole Interlobular | (–) | mPSL pulse PSL, CYC | PSL | 39 | 2 | Cr 1.7 |
| 4 | 80 | M | MPO 78 | MPA | 12.1 | 3.3 | 2 | 0.88 | 56 | 20 | Arteriole Interlobular | ILD | mPSL pulse PSL | PSL | 25 | 0 | Cr 2.9 |
| 5 | 58 | F | MPO 288 | MPA | 13.4 | 1 | 3 | 0.73 | 58 | 8 | Interlobular Arcuate | ILD | mPSL pulse PSL | PSL | 20 | 0 | Cr 1.1 |
| 6 | 70 | F | MPO 88 | MPA | 22.1 | 9.1 | 5 | 0.89 | 79 | 4 | Pulmonary hemorrhage | mPSL pulse | PSL | 19 | 0 | Cr 2.1 | |
| Interlobular | PSL | ||||||||||||||||
| Intestinal hemorrhage | PE | ||||||||||||||||
| 7 | 68 | F | P (+) | GPA | 11.9 | 1.1 | 4 | 0.5 | 0 | 40 | Arteriole Interlobular | ILD | PSL | PSL | 163 | 0 | Death (Intestinal perforation) |
| 8 | 57 | F | PR3 10 | GPA | 19.5 | 6.7 | 5 | 1.95 | 70 | 10 | Interlobular | Pulmonary tumor Neuritis | mPSL pulse PSL, CYC | PSL | 50 | 3 | Hemodialysis |
| 9 | 66 | M | MPO 359 | GPA | 5.7 | 0.6 | 4 | 0.13 | 9 | 12 | Interlobular | ILD Neuritis | mPSL pulse PSL, CYC | PSL MZB | 60 | 1 | Cr 1.8 |
| 10 | 62 | M | PR3 130 | GPA | 14.32 | 4 | 5 | 1.66 | 2 | 45 | Arteriole | Pulmonary tumor | mPSL pulse | PSL | 6 | 0 | Cr 2.6 |
| Interlobular | Celebral infarction | PSL, CYC | |||||||||||||||
| Arcuate | Neuritis Intestinal hemorrhage |
Crescents: the percentage of glomeruli with crescents. ILD: interstitial lung disease; PSL: prednisonone; mPLSpulse: intravenous methylprednisolone pulse therapy; CYC: cyclophosphamide; MZB: mizorbine; GPA: granulomatosis with polyangiitis; EU: ELISA unit; CRP: C-reactive protein; Cr: creatinine; MPO: myeloperoxidase; MPA: microscopic polyangiitis; PR3: proteinase 3.