Table 3.

Factors associated with reaching an outcome from Cox proportional hazards model.

Patient CharacteristicsHR95% CIp
Female sex1.491.25–1.78< 0.0001
Age, yrs1.031.02–1.04< 0.0001
Race
  White reference group1.001.00
  Black0.850.64–1.140.2868
  Hispanic1.050.85–1.310.6406
  Asian0.940.71–1.240.6473
  Other1.411.07–1.860.0141
Time taking therapy
  < 80% vs never taking therapy1.271.05–1.550.0142
  ≥ 80% vs never taking therapy1.080.76–1.520.6815
Laboratory data
  Baseline sUA level1.111.04–1.190.0027
  sUA at goal vs not at goal0.630.50–0.78< 0.0001
  Baseline GFR level1.010.99–1.010.1211
Comorbidities
  CV-related diseases1.150.93–1.420.2130
  Diabetes mellitus1.961.64–2.35< 0.0001
  Dyslipidemia0.920.77–1.120.3942
  Gout0.990.81–1.240.9922
  Heart failure1.391.04–1.840.0256
  Hypertension1.501.17–1.920.0015
  Obesity0.960.79–1.180.7068
  Osteoarthritis1.050.86–1.290.6181
  Rheumatoid arthritis1.460.84–2.540.1857
Concomitant medications
  Corticosteroids0.920.73–1.170.4923
  Colchicine1.080.82–1.420.5823
  NSAID0.850.72–1.010.0692
Hospitalizations1.331.12–1.590.0014
Role of therapy and treat to target goal < 6 mg/dl
  < 80% time receiving drug vs no TX1.271.05–1.550.01
  ≥ 80% time receiving drug vs no TX1.080.76–1.520.68
  sUA at goal vs not at goal0.630.5–0.78< 0.0001
  • sUA: serum uric acid; GFR: glomerular filtration rate; CV: cardiovascular; NSAID: nonsteroidal antiinflammatory drug; TX: treatment.