No. patients (%) with a worsening on the patient-reported outcome using the minimal clinically important difference (MCID). Values are given for patients who had data for both timepoints.
| Time Period | HAQ, MCID: 0.2 | RADAI, MCID: 1.0 | VAS Fatigue, MCID: 10 mm | VAS Global, MCID: 10 mm |
|---|---|---|---|---|
| T0–T1, n = 140 | 33 (23.6) | 66 (46.1) | 47, n = 138 (34.1) | 35 (25.0) |
| T1–T2, n = 133 | 25 (18.8) | 22 (16.3) | 30, n = 130 (23.1) | 30 (22.9) |
| T2–T3, n = 135 | 18 (11.1) | 18 (13.5) | 37, n = 147 (25.2) | 25 (18.6) |
| T0–T3, n = 142 | 27 (19) | 43 (30.3) | 36, n = 145 (24.8) | 40 (28.1) |
HAQ: Health Assessment Questionnaire; RADAI: Rheumatoid Arthritis Disease Activity Index; VAS: visual analog scale.