Table 1.

Data sources for validation data related to measures of 5 acute gout domains.

SourcenInclusionTreatment GroupsPublication (reference)
Merck Sharp & Dohme150Onset within 48 h, 1977
ARA criteria, at least moderate pain
Etoricoxib, indomethacin(7)
Pfizer402Onset within 48 h, 1977
ARA criteria, at least moderate pain
Celecoxib 50, 400/200, 800/400, indomethacin(8)
Regeneron225Onset within 48 h, 1977
ARA criteria, at least moderate pain
Indomethacin, rilonacept and indomethacin, rilonaceptNot published [NCT00855920]
Novartis (2 replicate studies)424Onset of acute flare within 5 days, 1977
ARA criteria, at least 3 flares within prior
12 mo, pain at least 50 mm on 100 mm VAS
Canakinumab 150 mg
SQ, triamcinolone 40 mg IM
(2)*
Auckland University of Technology20Observational study, acute gout flare at baseline, 1977 ARA criteriaNot applicable(3)
  • * Not published prior to data analyses and presentation but now published; dataset provided to investigators was a 90% random subsample of the main study dataset (n = 456). ARA: American Rheumatology Association; VAS: visual analog scale.