Table 3.

Cross-sectional association of widespread cartilage damage* and maximum synovitis scores from the whole knee.

Presence of Cartilage DamageAdjusted*** OR (95% CI) for CEMRI Max Synovitis Score
All Subjects, n = 342Excluding Subjects Taking Antiinflammatory Drugs, n = 285Excluding Subjects with Chondrocalcinosis on Radiography, n = 312
< 4 Subregions*1.00 (reference)1.00 (reference)1.00 (reference)
≥ 4 Subregions1.91 (1.24, 2.92)1.65 (1.03, 2.63)1.95 (1.26, 3.02)
< 6 Subregions**1.00 (reference)1.00 (reference)1.00 (reference)
≥ 6 Subregions1.94 (1.27, 2.74)1.67 (1.05, 2.63)1.89 (1.22, 2.93)
  • * Knees with 4 or more subregions with cartilage score of 2 or above were considered to have widespread cartilage damage.

  • ** Knees with 6 or more subregions with cartilage score of 2 or above were considered to have widespread cartilage damage.

  • *** Adjustment made for age, sex, and body mass index.

  • Synovitis score ≥ 1 in at least 1 of 11 sites. CEMRI: contrast-enhanced magnetic resonance imaging.