Echocardiographic and Doppler variables in patients with dermatomyositis and controls. Data are mean ± SD unless otherwise indicated.
| Variable | Patients, n = 51 | Controls, n = 51 | p |
|---|---|---|---|
| Left ventricular (LV) diameter, mm | 44.57 ± 4.36 | 45.24 ± 3.22 | NS |
| Left atrium diameter, mm | 30.39 ± 3.72 | 29.51 ± 2.80 | NS |
| Interventricular septum thickness, mm (range) | 9 (8, 10) | 9 (8, 10) | NS |
| Posterior wall thickness, mm (range) | 9 (8, 10) | 9 (8, 9) | NS |
| Aortic root diameter, mm (range) | 28 (26, 29) | 27 (26, 28) | NS |
| Ascending aorta diameter, mm (range) | 28 (27, 31) | 27 (26, 28) | NS |
| Main pulmonary artery diameter, mm (range) | 20 (19, 22) | 18 (17, 20) | NS |
| LV end-diastolic dimension, mm (range) | 45 (43, 47) | 45 (43, 48) | NS |
| LV end-systolic dimension, mm (range) | 28 (26, 30) | 28 (27, 30) | NS |
| LV end-diastolic volume, ml (range) | 92 (83, 104) | 93 (83, 106) | NS |
| LV end-systolic volume, ml | 30 (25, 34) | 30 (26, 35) | NS |
| Peak of early diastolic flow velocity (E), m/s | 0.72 ± 0.19 | 0.79 ± 0.16 | NS |
| Peak of late diastolic flow velocity (A), m/s | 0.77 ± 0.18 | 0.67 ± 0.13 | < 0.05 |
| E/A ratio | 0.97 ± 0.33 | 1.20 ± 0.28 | < 0.001 |
| Mitral annular early diastolic velocity (Em), cm/s | 7.78 ± 2.90 | 9.32 ± 2.10 | < 0.05 |
| Mitral annular late diastolic velocity (Am), cm/s (range) | 8 (7, 9) | 7.3 (6.8, 9.2) | NS |
| Em/Am ratio (range) | 0.89 (0.64, 1.22) | 1.18 (1.04, 1.29) | < 0.01 |
| E/Em ratio | 9.92 ± 2.82 | 8.67 ± 1.92 | < 0.05 |
| Deceleration time of flow velocity in early diastole (DT), ms | 231.75 ± 40.60 | 208.20 ± 26.30 | < 0.01 |
| Isovolumic relaxation time, ms | 81.06 ± 19.31 | 77.41 ± 11.32 | NS |
| LV stroke volume, ml | 61.16 ± 12.21 | 65.35 ± 10.83 | 0.069 |
| LV ejection fraction, % | 66.45 ± 6.81 | 68.20 ± 4.11 | 0.120 |
| LV fractional shortening, % (range) | 38 (34, 40) | 38 (36, 41) | 0.284 |
NS: not significant (p > 0.05).