Characteristic | Patients with AS, n = 47 | Controls, n = 22 | p |
---|---|---|---|
Age, yrs | 33 (28–36) | 29 (22–38) | 0.10 |
BASDAI | 3.7 (2.6–4.7) | NA | NA |
Disease duration, yrs | 6 (4–10) | NA | NA |
Male sex | 41 (87) | 13 (59) | 0.008 |
Body mass index, kg/m2 | 24.3 (22.5–26.6) | 23.3 (22.6–24.6) | 0.15 |
Smoking | 14 (30) | 6 (27) | 0.83 |
Mean blood pressure, mmHg | 92 (87–97) | 90 (87–92) | 0.13 |
Glucose, mmol/l | 4.7 (4.5–5.0) | 4.7 (4.4–4.9) | 0.72 |
eGFR, ml/min per 1.73 m2 | 121 (110–132) | 120 (99–141) | 0.15 |
Total cholesterol, mmol/l | 5.0 (4.2–5.8) | 4.8 (4.5–5.6) | 0.66 |
LDL cholesterol, mmol/l | 3.1 (2.4–3.8) | 2.8 (2.3–3.5) | 0.11 |
HDL cholesterol, mmol/l | 1.3 (1.2–1.5) | 1.7 (1.4–2.0) | 0.007* |
Total/HDL cholesterol | 3.7 (3.2–4.3) | 3.1 (2.5–3.7) | 0.01 |
Triglycerides, mmol/l | 0.9 (0.6–1.2) | 0.9 (0.7–1.2) | 0.48 |
hs-CRP, mg/l | 5.05 (2.57–16.50) | 0.88 (0.39–1.48) | < 0.001† |
Fibrinogen, g/l | 4.17 (3.40–5.23) | 3.09 (2.30–3.40) | < 0.001* |
↵* By Welch’s t test for untransformed data because of the non-uniformity of variances.
↵† By Welch’s t test for ln-transformed data because of the lack of normal distribution and the non-uniformity of variances. BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; NA: not applicable; eGFR: estimated glomerular filtration rate; LDL: low-density lipoprotein; HDL: high-density lipoprotein; hs-CRP: high-sensitivity C-reactive protein.