Drugs used before start of leflunomide (LEF) in patients with JIA.
| Drugs | |
|---|---|
| Corticosteroids, n (%) | 27 (62.7) |
| DMARD, n (%) | |
| Oral MTX | 43 (100) |
| MTX isolated | 30 (69.7) |
| Chloroquine diphosphate + MTX | 11 (25.5) |
| Sulfasalazine + MTX | 2 (4.6) |
| Mean time of MTX therapy, mos (range) | 60 (1.2–180) |
| Mean MTX dose (mg/week) prior to LEF, mean ± SD | 14.5 ± 4.5 |
JIA: juvenile idiopathic arthritis; DMARD: disease-modifying antirheumatic drug; MTX: methotrexate.