Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for radiographic progression according to different cutoffs of RAMRIS synovitis at baseline. AIC (Akaike’s information criteria) for model without and with the interaction with rheumatoid factor (RF) status.
| RAMRIS Synovitis (without RF interaction) | RAMRIS Synovitis (with RF interaction) | |||||
|---|---|---|---|---|---|---|
| Cutoff | Sensitivity | Specificity | PPV | NPV | AIC | AIC |
| 8 | 0.35 | 0.80 | 0.36 | 0.80 | 216.9 | 218.9 |
| 7 | 0.44 | 0.75 | 0.36 | 0.81 | 214.0 | 216.1 |
| 6 | 0.56 | 0.68 | 0.35 | 0.83 | 212.7 | 213.5 |
| 5 | 0.64 | 0.60 | 0.33 | 0.84 | 213.2 | 212.1* |
| 4 | 0.70 | 0.54 | 0.32 | 0.85 | 213.6 | 212.5 |
| 3 | 0.79 | 0.39 | 0.29 | 0.85 | 215.6 | 217.0 |
| 2 | 0.86 | 0.26 | 0.26 | 0.85 | 215.6 | 218.3 |
↵* Final model with lowest AIC (see Table 5 for sensitivity, specificity, and PPV and NPV for this model in both RF-positive and RF-negative patients; with OR adjusted for cohort effect). RAMRIS: Rheumatoid Arthritis Magnetic Resonance Imaging Score; RF: rheumatoid factor.