Age
  Mean ± SD60.0 ± 11.6
  Median (IQR)62.0 (54.0–69.0)
Sex
  Men, n (%)4 (5)
  Women, n (%)78 (95)
Disease duration (in years)
  Mean ± SD7.7 ± 7.1
  Median (IQR)6.0 (2.0–11.3)
Leroy subset, n (%)
  LSSc0 (0)
  LcSSc61 (74)
  DcSSc21 (26)
NVC pattern, n (%)
  Early29 (36)
  Active24 (29)
  Late24 (29)
  Normal — Aspecific changes5 (6)
Antibodies profile*, n (%)
  ACA39 (48)
  Anti-topo22 (27)
  Anti-RNA pol III3 (4)
  Pm-Scl1 (1)
Peripheral vascular therapy, n (%) “yes”
  Prostacyclins38 (46)
  Calcium antagonists71 (87)
  Endothelin receptor antagonists1 (1)
  Phosphodiesterase type 5 inhibitor0 (0)
Pulmonary-vascular therapy5 (6)
  Prostacyclins0 (0)
  Endothelin receptor antagonists4 (5)
  Phosphodiesterase type 5 inhibitor1 (1)
Lost to followup, n2
  Due to logistic reasons0
  Non-SSc-related reasons0
  SSc-related reasons2
  • * Missing for 1 patient for logistical reasons. NVC: nailfold videocapillaroscopy; IQR: interquartile range; LSSc: limited systemic sclerosis; LcSSc: limited cutaneous systemic sclerosis; DcSSc: diffuse cutaneous systemic sclerosis; ACA: anticentromere antibodies; anti-topo: antitopoisomerase; SSc: systemic sclerosis.