Summary of characteristics of patients with systemic sclerosis.
| Article (Reference) | N (%) | Women (%) | Ethnicity | Age (mean ± SD) | Disease Duration, yrs ± SD | Post (%) | Age at Menopause, yrs ± SD | BMI, mean ± SD | Skin Extent (%) |
|---|---|---|---|---|---|---|---|---|---|
| La Montagna 199519 | 22 | 19 (86) | W | Female 48.6 ± 10.7 | Female 14 | 9 (47) | 45.5 | NA | D 6 (27) |
| Male 54.6 ± 7.8 | Male 3 | L 5 (23) | |||||||
| I 11 (50) | |||||||||
| Neumann 200022 | 30 | 30 (100) | W | 56 ± 10 | 9.5 ± 7 | 24 (80) | NA | NA | D 19 (63) |
| L 11 (37) | |||||||||
| D’Amore 200523 | 25 | 24 (96) | NA | 53.28 | 6.4 | NA | NA | NA | NA |
| Frediani 200420 | 47 | 47 (100) | NA | 53.9 | NA | 27 (57) | NA | NA | NA |
| Frediani 200421 | 55 | 55 (100) | NA | 54.1 | Pre 5.4 | 30 (55) | NA | 22.5 ± 2.5 | D 18 (33) |
| Post 14.5 | L 23 (42) | ||||||||
| Carbone 199924 | 15 | 15 (100) | W 10 | NA | 9.87 | NA | NA | NA | D 9 (60) |
| B 5 | L 6 (40) | ||||||||
| Di Munno 199525 | 43 | 43 (100) | NA | 54.8 | 5.9 | 36 (84) | 46.4 ± 6.4 | L 23.7 ± 2.9 | D 9 (21) |
| I 23 ± 2.6 | |||||||||
| D 19.4 ± 1.5 | L 25 (58) | ||||||||
| I 9 (21) | |||||||||
| Hagdrup 198335 | 35 | 28 (80) | NA | 54.9 | 10 | NA | NA | NA | NA |
| Dovio 200827 | 60 | 48 (80) | NA | 58 | 3 | 37 (77) | NA | 25 | D 13 (22) |
| L 47 (78) | |||||||||
| Alexandersson 200734 | 24 | 18 (74) | W | 60 ± 15 | 15 ± 10 | 16 (89) | NA | 27 ± 5 | NA |
| La Montagna 199118 | 90 | 90 (100) | NA | 48* | 9* | 56 (62.2) | 45.5* | NA | D 34 (37) |
| L 34 (37) | |||||||||
| I 19 (23) | |||||||||
| SSS 3 (3) | |||||||||
| Souza 200629 | 43 | 43 (100) | NA | 62.3 ± 7.7 | 13.2 ± 8 | 43 (100) | 46.6 ± 6.6 | 24.01 ± 3.7 | NA |
| Serup 198332 | 37 | 30 (81) | NA | 55.7 | 8.9 | NA | NA | NA | NA |
| Sampaio-Barros 200528 | 61 | 61 (100) | 54 W | Pre 35.79 ± 6.77 | NA | 28 (45.9) | 46.7 ± 4.26 | Pre 23.34 ± 4.48 | D 21 (34.4) |
| 7 B. Brazilian | Post 54.21 ± 6.43 | Post 23.35 ± 4.98 | L 40 (65.6) | ||||||
| da Silva 199726 | 25 | 25 (100) | W | 48 ± 12 | 7 ± 7 | 13 (52) | NA | 27 ± 4 | D 4 (16) |
| L 19 (76) | |||||||||
| I 2 (8) | |||||||||
| Yuen 200830 | 159 | 130 (82) | NA | 58.3 ± 0.98 | 11.5 ± 0.7 | 63/79 | 46 ± 1.7 | 25.9 ± 0.6 | NA |
| Sampaio-Barros 200033 | 74 | 74 (100) | 64 W | D 40 | 10.7 | 40 (54) | 45 ± 5.7 | NA | D 24 (32) |
| 10 non W | L 50 | L 50 (68) | |||||||
| Zurek 200331 | 20 | 20 (100) | NA | 54.2 ± 11.0 | 5.8 ± 6.6 | NA | NA | NA | NA |
| Rios Fernandez 201016 | 48 | 48 (100) | NA | 59.1 ± 11.7* | NA | (75.8) | NA | 27.7 ± 5 | D (8.5) |
| L (91.5) |
↵* Median values. NA: not available; D: diffuse; L: limited; I: intermediate; Pre: premenopausal; Post: postmenopausal; W: white; B: black; SSS: scleroderma sine scleroderma; BMI: body mass index.