Summary of clinical and social outcomes in juvenile-onset (JoAS) versus adult-onset ankylosing spondylitis (AoAS).
| Domain | Characteristic | JoAS More Likely/Higher/Worse (Ref. No.) | Equal JoAS & AoAS (Ref. No.) | AoAS More Likely/Higher/Worse (Ref. No.) |
|---|---|---|---|---|
| Treatment | ||||
| NSAID use | (13) | |||
| Treatments | (5) | |||
| Medication use | (9, 14) | |||
| Employment | ||||
| Income | Better (6) | |||
| Socioeconomic status | (5) | |||
| Educational level | Better (6) | (12, 14) | Better (5) | |
| In school or employment | (13) | |||
| In full-time employment | (9) | |||
| Unemployable due to AS | (13) | |||
| Work disability | (6) | (14) | ||
| Health-related status | ||||
| HAQ | (14) | (7) | ||
| Limitation of lifestyle due to AS | (13) | |||
| BASG | (11) | (16) | ||
| PGA | NS (16) | |||
| Quality of life (SF-36) | (5) | (7) | ||
| ASQoL | (12) | (7) | ||
| Fatigue | BASDAI (12) | FACIT (7) | ||
| Modified Arthritis Impact Measurement Scales (AIMS; includes depression, anxiety, physical activity, pain, impact, social activity) | (9) | |||
| Social activity domain of AIMS | (9) | |||
NS: not statistically significant; AS: ankylosing spondylitis; ASQoL: AS quality of life index; FACIT: Functional Assessment of Chronic Illness Therapy Fatigue scale; HAQ: Health Assessment Questionnaire; PGA: Patient Global Assessment; SF-36: Medical Outcome Study Short Form-36; AIMS: Modified Arthritis Impact Measurement Scales; NSAID: nonsteroidal antiinflammatory drug; BASG: Bath AS Patient Global Score.