Baseline predictors of outcome in the ESPOIR cohort (multivariate analysis).
| Predictors | OR | (95% CI) |
|---|---|---|
| Three-yr radiographic progression | ||
| ACPA | 2.16 | (1.37 ± 3.40) |
| Baseline erosion score | 2.30 | (1.39 ± 3.79) |
| Five-yr HAQ disability | ||
| Baseline HAQ | 2.90 | (2.00–4.19) |
| Older age | 1.91 | (1.32–1.77) |
| Female sex | 1.60 | (1.02–2.50) |
| Baseline pain at rest | 1.69 | (1.17–2.44) |
| Prescription of at least 1 DMARD | ||
| ACPA | 4.85 | (2.46–9.56) |
| 2010 ACR/EULAR criteria | 2.52 | (1.58–4.01) |
| Baseline pain | 2.19 | (1.37–3.48) |
| Biologics prescription | ||
| ACPA | 3.12 | (1.80–5.43) |
| Baseline tender joint count | 2.34 | (1.51–3.61) |
| Baseline pain | 2.16 | (1.39–3.34) |
| Rheumatoid factor positivity | 1.90 | (1.07–3.35) |
ACPA: anticitrullinated protein antibodies; HAQ: Health Assessment Questionnaire; DMARD: disease-modifying antirheumatic drug; ACR: American College of Rheumatology; EULAR: European League Against Rheumatism.