Table 2.

Positive and negative predictive values of transthoracic echocardiogram (TTE) and pulmonary function tests (PFT) at detecting pulmonary arterial hypertension (PAH).

	PHAROS, n = 114				Cochin, n = 134				All, n = 248
	PPV	NPV	Sens	Spec	PPV	NPV	Sens	Spec	PPV	NPV	Sens	Spec
eRVSP > 35 mm Hg	0.63	0.85	0.93	0.42	0.38	1.0	1.0	0.87	0.58	0.97	0.94	0.73
eRVSP > 40 mm Hg	0.69	0.79	0.85	0.60	0.71	1.0	1.0	0.97	0.70	0.94	0.87	0.85
eRVSP > 45 mm Hg	0.74	0.75	0.78	0.71	0.83	0.96	0.50	0.99	0.75	0.90	0.74	0.91
eRVSP > 50 mm Hg	0.84	0.72	0.69	0.85	1.0	0.95	0.30	1.0	0.85	0.87	0.64	0.96
FVC%/DLCO% ≥ 1.6	0.53	0.52	0.80	0.24	0.30	0.99	0.90	0.83	0.47	0.90	0.81	0.65
FVC%/DLCO% ≥ 1.8	0.56	0.56	0.71	0.40	0.38	0.98	0.80	0.90	0.52	0.88	0.72	0.74
FVC%/DLCO% ≥ 2.0	0.68	0.62	0.61	0.69	0.50	0.97	0.60	0.95	0.65	0.85	0.61	0.87
DLCO% < 70	0.50	0.25	0.90	0.04	0.18	1.0	1.0	0.63	0.39	0.93	0.91	0.45
DLCO% < 60	0.50	0.38	0.83	0.11	0.36	1.0	1.0	0.85	0.47	0.92	0.86	0.63
DLCO% < 50	0.55	0.56	0.75	0.35	0.50	0.99	0.90	0.93	0.54	0.89	0.77	0.75

PPV: positive predictive value; NPV: negative predictive value; Sens: sensitivity; Spec: specificity; eRVSP: estimated right ventricular systolic pressure in mm Hg; FVC/DLCO: forced vital capacity/DLCO percent predicted ratio.