Association of block 2 haplotypes of TNIP1 with SLE.
| Haplotype | Total (%) | SLE (%) | Control (%) | GEE OR (95% CI) | p | |
|---|---|---|---|---|---|---|
| Block 2 | CCTTCGC | 737 (52.72) | 380 (55.72) | 357 (49.86) | Reference | |
| GTCCTAT | 279 (19.96) | 114 (16.72) | 165 (23.04) | 0.649 (0.491–0.858) | 0.0024* | |
| CCTCTGC | 236 (16.88) | 122 (17.89) | 114 (15.92) | 1.005 (0.743–1.361) | 0.9722 | |
| CCTTTGC | 81 (5.79) | 38 (5.57) | 43 (6.01) | 0.830 (0.518–1.331) | 0.4396 | |
| CCCCTGC | 20 (1.43) | 7 (1.03) | 13 (1.82) | 0.506 (0.191–1.341) | 0.1705 | |
| Other | CCCTCGC | 9 (0.64) | 4 (0.59) | 5 (0.70) | 0.822 (0.441–1.531) | 0.5367 |
| GTCCTAC | 8 (0.57) | 5 (0.73) | 3 (0.42) | |||
| CCTCTGT | 6 (0.43) | 2 (0.29) | 4 (0.56) | |||
| CCTTCGT | 4 (0.29) | 2 (0.29) | 2 (0.28) | |||
| GTCCTGC | 4 (0.29) | 1 (0.15) | 3 (0.42) | |||
| GTCCCAT | 3 (0.21) | 3 (0.44) | 0 (0.00) | |||
| GTCTTAT | 3 (0.21) | 1 (0.15) | 2 (0.28) | |||
| CCCTTGC | 2 (0.14) | 0 (0.00) | 2 (0.28) | |||
| GTCCTGT | 2 (0.14) | 1 (0.15) | 1 (0.14) | |||
| CCTCTAC | 1 (0.07) | 0 (0.00) | 1 (0.14) | |||
| CCTTTAT | 1 (0.07) | 0 (0.00) | 1 (0.14) | |||
| CTTTCGT | 1 (0.07) | 1 (0.15) | 0 (0.00) | |||
| GCCCTGC | 1 (0.07) | 1 (0.15) | 0 (0.00) |
↵* Significant association (p < 0.05). GEE: generalized estimating equations; SLE: systemic lupus erythematosus.