Table 3.

Progression of grade of MSG autoimmune lesions during followup.

Patient	Biopsy Interval (mo)	Infiltrating MNC/mm² of Tissue			MSG Biopsy Focus Score
Patient	Biopsy Interval (mo)	1st Biopsy	2nd Biopsy	Change, %	1st Biopsy	2nd Biopsy	Change, %
1	77.5	668	703	2.2	1.5	1.6	6.5
2	43.0	579	530	−8.5	1.0	1.00	0.00
3	36.0	146	154	5.5	1.3	1.0	−23.1
4	42.0	748	560	−25.1	2.3	2.6	14.5
5	36.0	1001	386	−61.4^†	1.9	1.5	−20.9
6	36.0	888	831	−6.4	2.3	2.3	−2.2
7	110.0	749	1105	47.5	2.7	3.3	24.7
8	36	431	1225	184.2^†	2.2	2.5	12.4
9	66.0	1369	1221	−10.8	3.1	3.0	−4.2
10	56.0	1827	1824	−0.2	4.6	5.0	9.4
11	52.0	908	1713	88.7^†	3.6	3.4	−5.3
12	48.0	1198	1648	37.6	3.4	3.2	−4.7
13^*	54.0	715	1214	69.8^†	1.8	3.1	71.1^†
14^*	42.0	4781	4817	0.8	5.6	6.9	24.1
15	109.0	2098	6383	204.2^†	4.0	11.6	190.0^†
16	58.0	3575	3318	−7.2	5.8	4.8	−17.5
17	89.0	2954	943	−68.1^†	6.9	2.0	−71.1^†
18^*	41.0	3500	3522	0.6	5.9	5.8	−1.4
19^*	36.0	6159	5737	−6.9	5.2	5.3	2.5
20^*	64.0	5809	6027	3.8	6.0	6.1	2.3
21	82.0	5110	5856	14.6	6.3	6.4	1.6
22	77.0	3868	3949	2.1	6.0	5.8	−3.3
23	107.5	4522	4556	0.8	5.0	5.1	2.0
24	82.0	2479	2667	7.6	4.0	4.0	0.0
25	42.0	7019	9604	36.8	8.2	11.4	39.0
26	54.0	4654	4739	1.8	5.3	5.8	8.4
27	89.0	4711	4462	−5.3	5.7	5.5	−3.0
28	64.0	5197	5220	0.4	4.8	4.9	2.1

↵† Changes over 60% or change in Tarpley score.
* Patients diagnosed with MSG-associated MALT lymphoma at the second biopsy. MSG biopsy focus score: number of lymphocytic foci per 4 mm² of tissue.