Table 2.

Demographic and disease characteristics in patients with diffuse idiopathic skeletal hyperostosis (DISH) by presence of syndesmophytes (n = 78).

Syndesmophytes, Mean (SD) or Frequency (%)
CharacteristicYes, n = 30No, n = 48p*
Age, yrs61.7 (8.0)63.7 (9.4)0.33
Sex, males/females (%)25 (83.3)/5 (16.7)32 (66.7)/16 (33.3)0.11
Age at diagnosis of psoriasis, yrs33.3 (14.8)42.9 (14.8)0.007
Age at diagnosis of PsA, yrs45.6 (12.6)49.4 (13.2)0.21
Duration of psoriasis, yrs28.4 (15.2)21.1 (13.7)0.03
Duration of PsA, yrs16.0 (12.2)14.5 (11.5)0.58
Body mass index33.9 (6.8)32.4 (4.8)0.40
Obesity (%)13 (76.5)18 (66.7)0.74
Diabetes (%)12 (41.4)9 (19.6)0.04
Hypertension (%)17 (56.7)22 (45.8)0.35
Angina (%)3 (10.3)0 (0.0)0.05
Myocardial infarction (since last visit, %)2 (8.3)0 (0.0)0.14
Enthesitis (%)1 (3.3)7 (14.6)0.14
Inflammatory back pain (%)2 (11.1)8 (22.2)0.47
Erythrocyte sedimentation rate20.4 (14.3)20.8 (15.4)0.91
C-reactive protein12.2 (10.2)10.1 (13.6)0.64
Elevated uric acid levels (%)5 (17.2)7 (15.2)1.00
Damaged joint count13.1 (16.4)11.1 (16.4)0.60
Radiographic damage (%)24 (80.0)42 (87.5)0.52
Modified Steinbrocker score35.1 (37.3)30.0 (41.6)0.59
Calcaneal spurs (%)26 (86.7)39 (81.3)0.53
Sacroiliitis (%)19 (65.5)18 (38.3)0.02
HLA-B*27 (%)5 (20.0)3 (7.0)0.13
HLA-C*06 (%)6 (24.0)7 (16.3)0.53
  • * Using t tests for continuous variables and Fisher’s exact test and chi-square test for categorical variables. PsA: psoriatic arthritis.