Association between baseline clinical markers and percentage changes in digital X-ray radiogrammetry (dxr-BMD) at 24 and 54 weeks, expressed as correlation coefficient calculated by Spearman analysis.
| Baseline | dxr-BMD Change 0–24 wks, r (n = 72) | p | dxr-BMD Change 0–54 wks, r (n = 52) | p | dxr-BMD Change 24–54 wks, r (n = 50) | p |
|---|---|---|---|---|---|---|
| Age | −0.24 | 0.04* | −0.21 | 0.14 | −0.17 | 0.23 |
| CRP | −0.06 | 0.64 | −0.17 | 0.23 | −0.18 | 0.20 |
| PASI | 0.06 | 0.60 | 0.11 | 0.46 | 0.08 | 0.58 |
| HAQ | −0.20 | 0.09 | −0.24 | 0.09 | −0.23 | 0.10 |
| Corticosteroid | −0.27 | 0.02* | −0.21 | 0.15 | 0.12 | 0.94 |
| Infliximab treatment | −0.03 | 0.23 | 0.04 | 0.35 | 0.26 | 0.07 |
| Early escape | −0.23 | 0.05 | −0.23 | 0.10 | 0.07 | 0.65 |
| Change in CRP | 0.09 | 0.45 | 0.14 | 0.34 | 0.20 | 0.16 |
| Change in PASI | 0.09 | 0.50 | −0.14 | 0.31 | 0.16 | 0.28 |
| Change in HAQ | 0.18 | 0.12 | −0.15 | 0.28 | 0.01 | 0.24 |
↵* p < 0.05. PASI: Psoriasis Area and Severity Index; HAQ: Health Assessment Questionnaire; CRP: C-reactive protein.