Table 2.

Four linear regression models for the relation between time-averaged Disease Activity Score (DAS) and change in Ratingen score, by anticitrullinated protein antibody (ACPA) status. Baseline Ratingen score was added as covariate to both models, age and sex were considered confounders.

ModelBeta (95% CI)p
ACPA-negative
  DAS3.32 (1.11–5.53)0.004
  Constant−3.575 (−9.69–2.55)0.249
  DAS3.87 (2.01–5.74)< 0.001
  Baseline score1.36 (0.98–1.75)< 0.001
  Age−0.11 (−0.24–0.01)0.068
  Sex−2.58 (−6.23–1.07)0.163
  Constant3.81 (−6.52–14.15)0.465
ACPA-positive
  DAS4.46 (2.70–6.22)< 0.001
  Constant−2.17 (−7.46–3.31)0.421
  DAS4.70 (2.96–6.45)< 0.001
  Baseline score0.81 (0.51–1.11)< 0.001
  Age−0.11 (−0.24–0.03)0.120
  Sex−1.77 (−4.98–1.44)0.278
  Constant3.54 (−5.62–12.69)0.447