Comparison of frequency of single-nucleotide polymorphisms (SNP) and genotype score between radiographic progression group and nonprogression group.
| SNP Associated with LDL Cholesterol | Radiographic Progression | No Radiographic Progression | p |
|---|---|---|---|
| rs688 | |||
| C vs T | < 0.001* | ||
| C/C (n = 174) | 38 (21.8) | 136 (78.2) | |
| C/T (n = 60) | 24 (40.0) | 36 (60.0) | |
| T/T (n = 12) | 7 (58.3) | 5 (41.7) | |
| rs4420638 | |||
| A vs G | < 0.001* | ||
| A/A (n = 182) | 39 (21.4) | 143 (78.6) | |
| A/G (n = 52) | 28 (53.8) | 24 (46.2) | |
| G/G (n = 12) | 4 (33.3) | 8 (66.7) | |
| Genotype score | 0 (0–1) | 1 (0–2) | < 0.001† |