OR (95% CI) for not being in remission off medication after 8 years of disease in relation to HLA-B27 and clinical characteristics in 399 patients with available outcome data from the Nordic JIA database.
| Total Cohort | Not in Remission After 8 Years of Followup | |||||||
|---|---|---|---|---|---|---|---|---|
| n | Prevalence n (%) | Crude | Model 1* | Model 2** | ||||
| OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |||
| HLA-B27-positive | 82 | 60 (73.2) | 2.2 (1.3–3.7) | 0.005 | 2.2 (1.3–3.8) | 0.004 | — | — |
| Any clinical sign of sacroiliitis† | 50 | 42 (84.0) | 4.1 (1.9–9.1) | < 0.001 | 4.3 (1.9–9.4) | < 0.001 | 3.6 (1.6–8.1) | 0.002 |
| Enthesitis†† | 38 | 29 (76.3) | 2.4 (1.1–5.2) | 0.028 | 2.5 (1.1–5.4) | 0.022 | 2.2 (1.0–4.8) | 0.051 |
| Hip arthritis | 96 | 70 (72.9) | 2.2 (1.3–3.6) | 0.002 | 2.2 (1.3–3.6) | 0.002 | 2.1 (1.3–3.5) | 0.004 |
↵* Adjusted for sex.
↵** Adjusted for sex and HLA-B27.
↵† At least 1 of 3 clinical signs of sacroiliitis, inflammatory back pain, sacroiliac (SI) pain (pain over the SI joints at palpation), or buttock pain during disease course.
↵†† Data available for 397 patients. JIA: juvenile idiopathic arthritis.