Clinical Signs | Sex (n) % | HLA-B27-positive 50 girls (%) 36 boys (%) | HLA-B27-negative 221 girls (%) 103 boys (%) | p* |
---|---|---|---|---|
Inflammatory back pain | Girls (15) 5.5 | 5/50 (10.0) | 10/221 (4.5) | 0.16 |
Boys (14) 10.1 | 10/36 (27.8) | 4/103 (3.9) | < 0.005 | |
Sacroiliac pain | Girls (13) 4.8 | 4/50 (8.0) | 9/221 (4.1) | 0.27 |
Boys (13) 9.3 | 9/36 (25.0) | 4/103 (3.9) | < 0.005 | |
Buttock pain | Girls (15) 5.5 | 3/50 (6.0) | 12/221 (5.4) | 0.74 |
Boys (11) 7.9 | 9/36 (25.0) | 2/103 (1.9) | < 0.005 | |
Any clinical sign of sacroiliitis** | Girls (29) 10.7 | 8/50 (16.0) | 21/221 (9.5) | 0.20 |
Boys (21) 15.1 | 15/36 (41.7) | 6/103 (5.8) | < 0.005 | |
Enthesitis | Girls (19) 7.0 | 4/50 (8.0) | 15/221 (6.8) | 0.48 |
Boys (30) 21.6 | 12/36 (33.3) | 8/103 (7.8) | < 0.005 | |
Tenosynovitis | Girls (51) 18.8 | 12/50 (24.0) | 39/221 (17.6) | 0.12 |
Boys (35) 25.2 | 14/36 (38.9) | 21/103 (20.4) | 0.04 | |
Hip arthritis | Girls (65) 24.0 | 14/50 (28.0) | 51/221 (23.1) | 0.47 |
Boys (34) 24.5 | 12/36 (33.3) | 22/103 (21.4) | 0.18 | |
Arthritis in small joints of feet† | Girls (150) 55.4 | 28/50 (56.0) | 122/221 (55.2) | 0.52 |
Boys (70) 50.4 | 20/36 (55.6) | 50/103 (48.5) | 0.30 |
↵* Fisher’s exact test, HLA-B27-positive versus negative JIA patients.
↵** At least 1 of 3 clinical signs of sacroiliitis, inflammatory back pain, sacroiliac pain (pain over the sacroiliac joints at palpation), or buttock pain during disease course.
↵† Arthritis in tarsal, metatarsophalangeal, toe, or subtalar joints during disease course.