Characteristics of patients in this study.
| Characteristic | Active Renal, n = 20 | Active Nonrenal, n = 16 | Longterm Remission n = 14 | Total, n = 50 |
|---|---|---|---|---|
| Sex | ||||
| Female | 8 | 8 | 4 | 20 |
| Male | 12 | 8 | 10 | 30 |
| Age, yrs* | 60 (48–67; 26–80) | 50 (34–57; 17–71) | 48 (40–56; 19–63) | 52 (44–61; 17–80) |
| Disease | ||||
| GPA | 17 | 13 | 10 | 40 |
| MPA | 1 | 0 | 1 | 2 |
| CSS | 0 | 3 | 3 | 6 |
| Unknown | 2 | 0 | 0 | 2 |
| ANCA specificity | ||||
| PR3 | 17 | 11 | 7 | 35 |
| MPO | 1 | 1 | 2 | 4 |
| Disease duration, yrs* | 6.9 (3.6–9.1; 1.2–18) | 4.9 (3.0–8.8; 0.6–21) | 5.2 (2.9–11; 1.9–28) | 6.5 (3.2–9.8; 0.6–28) |
| GFR* | 59 (48–71; 24–78) | 87 (74–99; 55–175) | 71 (51–86; 25–115) | 70 (52–86; 24–175) |
| Treatment: yes/no** | ||||
| Active | 15/4 | 14/2 | NA | 29/6 |
| Remission | 33/14 | 34/4 | 41/1 | 108/19 |
| Proteinuria: yes/no** | ||||
| Active | 14/5 | 2/12 | NA | 16/17 |
| Remission | 14/31 | 4/29 | 9/31 | 27/91 |
| Hematuria: yes/no** | ||||
| Active | 15/3 | 6/8 | NA | 21/11 |
| Remission | 13/31 | 7/25 | 8/30 | 28/86 |
| RBC: yes/no** | ||||
| Active | 15/3 | 4/8 | NA | 19/11 |
| Remission | 10/28 | 8/20 | 9/31 | 27/78 |
| RBC casts: yes/no** | ||||
| Active | 8/8 | 1/10 | NA | 9/18 |
| Remission | 3/28 | 0/26 | 1/35 | 4/89 |
↵* For age, disease duration, and GFR, numbers indicate median (25%–75%; range).
↵** Data on treatment and urinalyses are reported per sample, stratified by the presence or absence of active vasculitis. Because of missing data, numbers do not always sum to the numbers of patients in the group. GPA: granulomatosis with polyangiitis; MPA: microscopic polyangiitis; CSS: Churg-Strauss syndrome; PR3: proteinase-3; MPO: myeloperoxidase; GFR: glomerular filtration rate, ml/min per 1.73 m2. NA: not applicable; ANCA: antineutrophil cytoplasmic antibody; RBC: red blood cells.