Comparison of ACR/EULAR Boolean remission criteria with 8 other criteria according to rheumatoid arthritis (RA) indices in 720 RA patients in the ESPOIR cohort (all p < 0.001).
| Indices | In Remission According to Index* | Boolean Criteria (ACR/EULAR) | SDAI Criteria (ACR/EULAR) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 93 (12.9%)* Remission (R) | 627 (87.1%)* Non-Remission (N) | Agreement, % | Kappa 95% CI) | Agreement, | % Kappa (95% CI) | ||||
| R** | N** | R** | N** | ||||||
| SDAI (%) | 123 (17.1) | 89 (95.7) | 4 (4.3) | 34 (5.4) | 593 (94.6) | 94.7 | 0.79 (0.73–0.86) | NA | NA |
| DAS28 (%) | 234 (32.5) | 91 (97.8) | 2 (2.2) | 143 (22.8) | 484 (77.2) | 79.9 | 0.46 (0.39–0.52) | 94.7 | 0.79 (0.73–0.86) |
| CDAI (%) | 129 (17.9) | 88 (94.6) | 5 (5.4) | 41 (6.5) | 586 (93.5) | 93.6 | 0.76 (0.69–0.82) | 98.6 | 0.95 (0.92–0.98) |
| RAPID3R (%) | 181 (25.1) | 86 (92.5) | 7 (7.5) | 95 (15.2) | 532 (84.8) | 85.8 | 0.55 (0.48–0.62) | 85.6 | 0.57 (0.50–0.64) |
| RAPID3R+SJ1 (%) | 131 (18.2) | 86 (92.5) | 7 (7.5) | 45 (7.2) | 582 (92.8) | 92.8 | 0.73 (0.66–0.80) | 91.6 | 0.71 (0.64–0.78) |
| RAPID3R+SJ1+D1 (%) | 112 (15.6) | 80 (86.0) | 13 (14.0) | 32 (5.1) | 595 (94.9) | 93.7 | 0.74 (0.67–0.81) | 92.1 | 0.71 (0.64–0.78) |
| RAPID3R+SJ0 (%) | 107 (14.9) | 72 (77.4) | 21 (22.6) | 35 (5.6) | 592 (94.4) | 92.2 | 0.67 (0.60–0.75) | 91.7 | 0.69 (0.62–0.76) |
| RAPID3R+SJ0+D1 (%) | 92 (12.8) | 68 (73.1) | 25 (26.9) | 24 (3.8) | 603 (96.2) | 93.2 | 0.70 (0.61–0.78) | 91.8 | 0.68 (0.60–0.75) |
↵* Percentage of 720 patients.
↵** Percentage of 93 patients in remission by Boolean criteria.
*** Percentage of 627 patients not in remission by Boolean criteria. SDAI: Simplified Disease Activity index; CDAI: Clinical Disease Activity Index; DAS28: Disease Activity Score-28; RAPID3: Routine Assessment of Patient Index Data; ACR: American College of Rheumatology; EULAR: European League Against Rheumatism.