Table 2.

Results of single variable and multivariable logistic regression analysis for the association between hand bone mineral density at baseline. OR refers to risk for hand bone mineral density below median.

Factor	Single Variable Analysis		Multivariable Analysis
Factor	OR (95% CI)	p	OR (95% CI)	p
Age, yrs	0.96 (0.91–1.01)	0.089
Disease category^*	1.84 (1.09–3.12)	0.023	2.24 (0.97–5.18)	0.060
Sex^**	3.66 (1.22–11.0)	0.021
Weight, kg	1.05 (1.01–1.10)	0.016	1.06 (1.01–1.12)	0.042
ESR, mm/h	0.98 (0.95–1.00)	0.060
CRP, mg/l	0.99 (0.97–1.01)	0.281
DAS	0.65 (0.40–1.07)	0.089
DAS28-CRP	0.89 (0.58–1.28)	0.616
Fatigue, 0–10 scale	0.96 (0.75–1.22)	0.732
GVAS, 0–100 mm	0.92 (0.72–1.17)	0.492
HAQ, 0–3 scale	0.67 (0.30–1.48)	0.320
Pain, 0–10 scale	1.16 (0.92–1.45)	0.203
TJC, 0–28 joints	0.99 (0.93–1.05)	0.659
SJC, 0–28 joints	1.02 (0.95–1.09)	0.645
Stiffness, min	1.00 (0.99–1.01)	0.500
Bone ALP, μg/l	0.87 (0.77–0.99)	0.031	0.76 (0.620–0.94)	0.010
PINP, μg/l	0.97 (0.94–0.99)	0.021
OC[1–49], μg/l	0.92 (0.83–1.02)	0.099
CTX-I, μg/l	0.32 (0.00–0.48)	0.013
NTX-I, nmolBCE/mmol Cr	0.97 (0.95–0.99)	0.026
fDPD, nmol/mmol Cr	0.88 (0.77–1.01)	0.070

↵* If disease category is psoriatic arthritis.
↵** If sex is male. ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; DAS28-CRP: 28-joint Disease Activity Score using the CRP; GVAS: global visual analog scale (0 = worst imaginable health state to 100 = best imaginable health state); HAQ: Health Assessment Questionnaire scale (0 = no difficulty to 3 = unable to perform activity); TJC: tender joint count; SJC: swollen joint count; serum bone ALP: bone-specific alkaline phosphatase; serum PINP: procollagen type-I N-propeptide; serum OC[1–49]: intact osteocalcin; serum CTX-I: C-terminal cross-linking telopeptide of type-I collagen; urine NTX-I: N-terminal cross-linking telopeptide of type-I collagen; urine fDPD: free deoxypyridinoline crosslinks;