Mean (median) values of demographic, articular, global, self-report questionnaire, and indices of 720 patients from the ESPOIR cohort at baseline and according to whether patients met ACR/EULAR Boolean criteria for remission 6 months after baseline. Data were analyzed according to mean values and t test for normally distributed variables, and median values and Mann-Whitney test for variables that were not normally distributed.
| Variables | Baseline, All Patients | Baseline Status of Patients in Remission/Not in Remission 6 Months Later, According to Boolean Remission Criteria | ||
|---|---|---|---|---|
| Remission | Not Remission | p | ||
| No. patients | 720 | 93 | 627 | NA |
| Age, yrs, mean (± SE) | 48.2 (12.4) | 44.9 (12.7) | 48.7 (12.3) | 0.007 |
| Sex, % female | 76.2 | 80.6 | 75.6 | 0.29 |
| Disease duration, mo, median (IQR) | 4.8 (2.9–7.0) | 4.0 (2.5–6.1) | 4.9 (3.0–7.1) | 0.09 |
| Swollen joint counts (0–28), median (IQR) | 6 (3–10) | 4 (2–10) | 6 (3–10) | 0.013 |
| Tender joint counts (0–28), median (IQR) | 6 (3–12) | 4 (2–8) | 7 (3–13) | < 0.001 |
| Physician global (0-100), mean (± SE) | 50.8 (22.2) | 44.0 (22.9) | 51.8 (21.9) | 0.0015 |
| ESR, mm/h, median (IQR) | 22 (12–38) | 19 (12–35) | 22 (12–39) | 0.55 |
| CRP, mg/l, median (IQR) | 0.9 (0.5–2.5) | 0.9 (0.3–2) | 0.9 (0.5–2.5) | 0.247 |
| HAQ (0–3 scale), median (IQR) | 0.875 (0.375–1.375) | 0.625 (0.25–1.25) | 0.875 (0.375–1.5) | 0.011 |
| VAS pain (0–100), mean (IQR) | 46.0 (22.2) | 36.9 (21.2) | 47.4 (22.1) | < 0.0001 |
| Patient global (0–100), median (IQR) | 60 (45–80) | 54.5 (31.5–75.5) | 65.5 (47–80) | 0.016 |
| DAS28 (0-10), mean (± SE) | 5.1 (1.3) | 4.7 (1.2) | 5.2 (1.2) | 0.0005 |
| SDAI (0-86), mean (± SE) | 29.2 (14.4) | 24.3 (14.6) | 29.9 (14.2) | 0.0005 |
| CDAI (0-76), mean (± SE) | 26.9 (13.4) | 22.5 (14.0) | 27.5 (13.2) | 0.0007 |
| RAPID3 (0-30), mean (± SE) | 13.8 (5.7) | 11.7 (5.8) | 14.1 (5.6) | 0.0002 |
IQR: interquartile range; SDAI: Simplified Disease Activity Index; DAS28: Disease Activity Score-28; RAPID3: Routine Assessment of Patient Index Data; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; VAS: visual analog scale; ACR: American College of Rheumatology; EULAR: European League Against Rheumatism; HAQ: Health Assessment Questionnaire; CDAI: Clinical Disease Activity Index; NA: not applicable.