Timing of patient-reported outcome (PRO) assessments.
| PRO Assessment | Time, weeks | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 4 | 6 | 8 | 12 | 16 | 20 | 24 | |
| Pain, 100 mm VAS* | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Disease activity, 100 mm VAS** | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| HAQ-DI*** | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Short Form-36 health survey† | ✓ | ✓ | ||||||||
| FACIT-fatigue†† | ✓ | ✓ | ✓ | |||||||
↵* 0 = no pain, 100 = unbearable pain, for patient assessment of arthritis pain.
↵** 0 = very well, 100 = very poor, for patient global assessment of disease activity.
↵*** Health Assessment Questionnaire-Disability Index to measure patient's physical function.
↵† To measure aspects of health-related quality of life.
↵†† To measure patient's fatigue. VAS: visual analog scale; FACIT: Functional Assessment of Chronic Illness Therapy.