Demographics and individual TST/QFT-GIT results over the study period in 12 patients with no evidence of LTBI at baseline. All the patients showed a negative QFT-GIT at baseline except no. 6, who displayed an indeterminate result.
| QFT-GIT (IU/ml) Responses over Study Period (months since biologic onset) | |||||||
|---|---|---|---|---|---|---|---|
| Patient | Age, yrs/Sex | Diagnosis | TNF Inhibitor | 3 | 6 | 12 | 18 |
| 1 | 68 M | PsA | ETA | Pos (1.03) | Pos (1.55) | Pos (0.57) | Pos (0.75) |
| 2 | 37 F | RA | ADA | Neg | Neg | Pos (3.04) | Neg |
| 3 | 42 M | AS | ADA | Neg | Neg | Neg | Pos (0.44) |
| 4 | 44 F | RA | ADA | Pos (3.99) | Pos (1.16) | Neg | Neg |
| 5 | 43 F | PsA | INF | Neg | Neg | Pos (0.53) | Neg |
| 6 | 70 F | RA | ETA | Neg | Pos (0.53) | Pos (1.06) | Neg |
| 7 | 40 M | AS | ADA | Neg | Neg | Pos (2.47) | Neg |
| 8 | 47 F | PsA | ETA | Pos (0.93) | Neg | Neg | Neg |
| 9 | 40 M | PsA | ETA | Pos (0.64) | Neg | Neg | Neg |
| 10 | 34 M | PsA | ETA | Neg | Neg | Ind | Pos (1.53) |
| 11 | 51 M | AS | ETA | Ind | Neg | Pos (4.64) | Pos (0.38) |
| 12 | 45 M | PsA | ADA | Neg | Pos (0.50) | Neg | Neg |
TST: tuberculin skin test; QFT-GIT: QuantiFeron-TB Gold In-Tube; TNF: tumor necrosis factor; TB: tuberculosis; AS: ankylosing spondylitis; PSA: psoriatic arthritis; RA: rheumatoid arthritis; ADA: adalimumab; ETA: etanercept; INF: infliximab; Ind: indeterminate.