Table 3.

Disease course pattern and therapeutic strategies used in 132 patients with SJIA. Values are number of patients (percentage) or median (interquartile range).

Early OnsetLate Onsetp
Duration of followup, mo, median (IQR)86 (49–120)72 (48–123)NS
Course pattern
  Monocyclic3 (16)28 (25)NS
  Intermittent3 (16)22 (19)NS
  Persistent13 (68)63 (56)NS
Treatment
  Corticosteroids19 (100)106 (94)NS
  Methotrexate17 (89)98 (87)NS
  Biologic agents11 (57)33 (29)0.01
  Anti-tumor necrosis factor11 (57)33 (29)0.01
  Anti-interleukin 10 (0)3 (3)NS
  Anti-interleukin 61 (5)4 (4)NS
  Costimulatory inhibition1 (5)1 (1)NS
  B cell depletion0 (0)3 (3)NS
  • NS: nonsignificant.