PEST | ToPAS | PASE47 | |||||||
---|---|---|---|---|---|---|---|---|---|
True-Positive, n = 112–115 | False-Negative, n = 20 | p | True-Positive, n = 89–91 | False-Negative, n = 30–31 | p | True-Positive, n = 89–92 | False-Negative, n = 43 | p | |
Disease activity at the time of evaluation | |||||||||
TJC | 11.4 ± 12.3 | 4.4 ± 2.8 | 0.02 | 8.8 ± 11.8 | 7.0 ± 10.1 | 0.46 | 11.6 ± 12.5 | 6.3 ± 6.4 | 0.05 |
SJC | 4.9 ± 6.9 | 1.9 ± 1.6 | 0.09 | 4.1 ± 7.1 | 2.1 ± 3.0 | 0.14 | 5.1 ± 0.2 | 2.4 ± 2.4 | 0.08 |
Dactylitis | 29 (25) | 0 | < 0.01 | 25 (28) | 1 (3) | < 0.01 | 26 (28) | 3 (7) | < 0.01 |
Heel enthesitis | 36 (31) | 3 (15) | 0.11 | 27 (30) | 11 (35) | 0.45 | 30 (33) | 10 (23) | 0.18 |
Nail pitting | 61 (54) | 7 (35) | 0.09 | 54 (61) | 9 (30) | 0.003 | 44 (49) | 24 (56) | 0.31 |
PsQOL | 8.4 ± 6.0 | 5.7 ± 5.8 | 0.05 | 8.7 ± 5.6 | 6.1 ± 5.8 | 0.02 | 10.1 ± 5.3 | 4.7 ± 7.2 | < 0.001 |
PGA | 1.5 ± 1.0 | 1.4 ± 1.0 | 0.77 | 1.5 ± 1.0 | 1.7 ± 1.1 | 0.46 | 1.5 ± 1.0 | 1.3 ± 0.9 | 0.19 |
BSA | 4.5 ± 9.9 | 1.6 ± 1.8 | 0.20 | 4.3 ± 10.3 | 3.3 ± 6.1 | 0.63 | 5.1 ± 10.8 | 2.1 ± 3.0 | 0.08 |
PsA features (patient-reported, past or present) | |||||||||
Joint pain or swelling | 114 (99) | 19 (95) | 0.28 | 90 (99) | 30 (97) | 0.45 | 92 (100) | 41 (95) | 0.10 |
Inflammatory back pain | 52 (45) | 7 (35) | 0.47 | 42 (46) | 14 (45) | 1.00 | 50 (54) | 10 (23) | < 0.001 |
Morning stiffness ≥ 30 min | 90 (78) | 14 (68) | 0.40 | 68 (74) | 22 (70) | 0.81 | 79 (86) | 20 (48) | < 0.001 |
Sausage digits | 61 (53) | 3 (15) | < 0.01 | 53 (58) | 3 (10) | < 0.001 | 52 (57) | 12 (28) | < 0.01 |
Heel tenderness | 57 (50) | 6 (30) | 0.15 | 46 (51) | 16 (52) | 1.00 | 50 (54) | 14 (33) | 0.03 |
Nail pitting | 67 (58) | 7 (35) | 0.09 | 61 (67) | 9 (29) | 0.003 | 49 (53) | 24 (56) | 0.85 |
No. PsA features | 3.6 ± 1.3 | 2.7 ± 1.0 | < 0.001 | 4.0 ± 1.2 | 2.8 ± 1.2 | < 0.001 | 4.0 ± 1.2 | 2.7 ± 1.2 | < 0.001 |
Yrs of arthritis symptoms | 15.6 ± 19.0 | 8.8 ± 10.5 | 0.12 | 14.4 ± 14.4 | 8.0 ± 8.4 | 0.02 | 15.2 ± 19.3 | 12.5 ± 13.0 | 0.38 |
Immunomodulator, current | 55 (48) | 8 (40) | 0.34 | 46 (51) | 10 (32) | 0.28 | 46 (50) | 17 (40) | 0.16 |
PsA: psoriatic arthritis; TJC: tender joint count; SJC: swollen joint count; PsQOL: Psoriatic arthritis Quality of Life; PGA: physician global assessment; BSA: body surface area; PEST: Psoriasis Epidemiology Screening project; ToPAS: the Toronto Psoriatic Arthritis Screen; PASE: Psoriatic Arthritis Screening and Evaluation.