Table 5.

Alterations in the SLE-related antibodies before and after 12 months of treatment. Values are mean (SD) unless otherwise indicated.

SLE-related AntibodiesVitamin D GroupPlacebo Groupp
Anti-dsDNA, U/ml
  Baseline55.8 (14.1)55.6 (14.2)0.67
    % positive8685
  12 months32.8 (12.7)44.8 (13.9)0.05
    % positive6782
Anti-Sm, U/ml
  Baseline10.79 (9.01)10.75 (8.81)0.66
    % positive2524
  12 months8.21 (7.82)9.59 (7.94)0.05
    % positive1622
C4 (mg/l)
  Baseline0.166 (0.091)0.168 (0.089)0.65
  12 months0.270 (0.071)0.179 (0.079)0.05
Anticardiolipin IgG, GPL IU/ml
  Baseline11.1 (2.3)11.3 (2.5)0.66
    % positive2221
  12 months10.9 (2.1)11.1 (2.0)0.59
    % positive1819
Anticardiolipin IgM, GPL IU/ml
  Baseline7.9 (2.4)7.8 (2.2)0.61
    % positive1817
  12 months7.5 (2.1)7.6 (2.5)0.65
    % positive1416
  • ANA: antinuclear antibodies.