Alterations in the SLE-related antibodies before and after 12 months of treatment. Values are mean (SD) unless otherwise indicated.
| SLE-related Antibodies | Vitamin D Group | Placebo Group | p |
|---|---|---|---|
| Anti-dsDNA, U/ml | |||
| Baseline | 55.8 (14.1) | 55.6 (14.2) | 0.67 |
| % positive | 86 | 85 | |
| 12 months | 32.8 (12.7) | 44.8 (13.9) | 0.05 |
| % positive | 67 | 82 | |
| Anti-Sm, U/ml | |||
| Baseline | 10.79 (9.01) | 10.75 (8.81) | 0.66 |
| % positive | 25 | 24 | |
| 12 months | 8.21 (7.82) | 9.59 (7.94) | 0.05 |
| % positive | 16 | 22 | |
| C4 (mg/l) | |||
| Baseline | 0.166 (0.091) | 0.168 (0.089) | 0.65 |
| 12 months | 0.270 (0.071) | 0.179 (0.079) | 0.05 |
| Anticardiolipin IgG, GPL IU/ml | |||
| Baseline | 11.1 (2.3) | 11.3 (2.5) | 0.66 |
| % positive | 22 | 21 | |
| 12 months | 10.9 (2.1) | 11.1 (2.0) | 0.59 |
| % positive | 18 | 19 | |
| Anticardiolipin IgM, GPL IU/ml | |||
| Baseline | 7.9 (2.4) | 7.8 (2.2) | 0.61 |
| % positive | 18 | 17 | |
| 12 months | 7.5 (2.1) | 7.6 (2.5) | 0.65 |
| % positive | 14 | 16 |
ANA: antinuclear antibodies.