Multivariate linear regression analyses at baseline (T0), 2-year followup (T2y), and 5-year followup (T5y) with WOMAC pain (0–100 scale) as dependent variable. Difference refers to knee and contralateral knee and sum to left + right knee.
| ß (95% CI) | p | |
|---|---|---|
| Radiographic feature T0 | ||
| Medial JSW (difference) | 4.36 (1.26, 7.45) | 0.01 |
| Demographic | ||
| BMI T0 | 0.80 (0.35, 1.25) | 0.0006 |
| Radiographic feature T2y | ||
| Bone density (difference) | 1.14 (0.21, 2.07) | 0.02 |
| Demographic | ||
| BMI T2y | 0.79 (0.31, 1.26) | 0.001 |
| ESR T0 | 0.34 (0.05, 0.62) | 0.02 |
| Radiographic feature T5y | ||
| Minimum JSW (sum) | −1.28 (−2.26, −0.29) | 0.01 |
| Osteophyte area (sum) | 3.49 (0.73, 6.24) | 0.01 |
| Demographic | ||
| BMI T5y | 0.81 (0.39, 1.23) | 0.0002 |
WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index for pain; ß: regression coefficient; JSW: joint space width; BMI: body mass index; ESR: erythrocyte sedimentation rate.