Baseline characteristics of the study patients.
Characteristics | Persistent LAC and/or aPL ≥ 40 U, n = 17 | LAC and aPL Transiently Positive or Negative, n = 73 | p* |
---|---|---|---|
Age at last aPL/LAC, mean (SD) yrs | 41 (16) | 39 (13) | 0.80 |
Women, n (%) | 14 (83) | 69 (95) | 0.12 |
Race, n (%) African American** | 3 (27) | 41 (64) | 0.02 |
Ethnicity, n (%) Hispanic | 12 (75) | 32 (46) | 0.03 |
HCQ, n (%) | 11 (65) | 65 (89) | 0.02 |
Aspirin, n (%) | 6 (35) | 14 (19) | 0.29 |
Prednisone, n (%) | 11 (65) | 60 (83) | 0.10 |
Immunosuppressives, n (%) | 5 (29) | 35 (49) | 0.18 |
Anticoagulation ever for arterial or venous thrombosis or for pregnancy complication, n (%) | 7 (41) | 13 (18) | 0.02 |
Duration on HCQ, mo, median (IQR) | 49 (31, 61) | 36 (19, 56) | 0.38 |
Time between first and last aPL/LAC measurement, mo, median (IQR) | 18 (9, 42) | 25 (13, 38) | 0.60 |
Charlson comorbidity, median (IQR) | 4.0 (2.0, 7.0) | 5.0 (2.0, 7.0) | 0.81 |