Table 2.

Baseline characteristics of the study patients.

CharacteristicsPersistent LAC and/or aPL ≥ 40 U, n = 17LAC and aPL Transiently Positive or Negative, n = 73p*
Age at last aPL/LAC, mean (SD) yrs41 (16)39 (13)0.80
Women, n (%)14 (83)69 (95)0.12
Race, n (%) African American**3 (27)41 (64)0.02
Ethnicity, n (%) Hispanic12 (75)32 (46)0.03
HCQ, n (%)11 (65)65 (89)0.02
Aspirin, n (%)6 (35)14 (19)0.29
Prednisone, n (%)11 (65)60 (83)0.10
Immunosuppressives, n (%)5 (29)35 (49)0.18
Anticoagulation ever for arterial or venous thrombosis or for pregnancy complication, n (%)7 (41)13 (18)0.02
Duration on HCQ, mo, median (IQR)49 (31, 61)36 (19, 56)0.38
Time between first and last aPL/LAC measurement, mo, median (IQR)18 (9, 42)25 (13, 38)0.60
Charlson comorbidity, median (IQR)4.0 (2.0, 7.0)5.0 (2.0, 7.0)0.81
  • * p values in bold type indicate statistical significance.

  • ** Race information not available for 15 patients. aPL: antiphospholipid antibodies; LAC: lupus anticoagulant; HCQ: hydroxychloroquine; IQR: interquartile range.