Table 4.

Summary of variables in the logistic regression model for “increase in therapy” (strict definition) at 3 and 6 months. Model had correct classification of 76.2% (p < 0.0005) at 3 months and 79.3% (p < 0.0005) at 6 months. Anticitrullinated protein antibody status was not included in the model at 6 months as it greatly increased the number of excluded cases due to missing data.

	Age	TJC	SJC	ESR	CRP	Patient Global Assessment	HAQ-DI	Pain Today	Physician Global Assessment	DAS28
Exp(B) (95% CI), 3 months	0.989 (0.975, 1.002)	1.019 (0.985, 1.055)	1.050 (0.998, 1.105)	1.008 (0.991, 1.024)	1.005 (0.984, 1.026)	1.007 (0.996, 1.017)	0.541 (0.357, 0.820)	1.116 (0.995, 1.251)	1.460 (1.316, 1.620)	0.999 (0.855, 1.167)
p	0.089	0.273	0.061	0.372	0.638	0.229	0.004	0.060	< 0.0005	0.987
Exp(B) (95% CI), 6 months	^*	0.997 (0.962, 1.033)	1.098 (1.040, 1.160)	0.985 (0.968, 1.002)	^**	1.015 (1.004, 1.027)	0.872 (0.569, 1.336)	0.996 (0.885, 1.122)	1.249 (1.106, 1.412)	1.235 (1.029, 1.481)
p	—	0.868	0.001	0.083	—	0.007	0.529	0.952	< 0.0005	0.023

↵* Age did not reach the p value < 0.1 cutoff point at 6 months.
↵** CRP did not reach the p value < 0.1 cutoff point at 6 months. For definitions see Table 2.