Table 1.

Characteristics of women exposed to nonselective COX inhibitors or COX-2 selective inhibitors, and unexposed women*.

VariableExposed to Nonselective COX Inhibitors, n = 5153Exposed to COX-2 Selective Inhibitors, n = 114Unexposed, n = 105,537
Age, yrs, mean ± SD30.10 ± 6.22 (p < 0.001)32.66 ± 6.23 (p < 0.001)28.53 ± 5.95
Pregestational diabetes mellitus, n; %120; 2.3 (p < 0.001)3; 0.3 (p = 0.083)944; 0.9
Inflammatory disease, n %5; 0.1 (p = 0.620)3; 2.6 (p < 0.001)87; 0.1
Parity, mean ± SD1.30 ± 2.99 (p < 0.001)4.37 ± 2.85 (p = 0.005)3.68 ± 2.61
Ethnic group**, n; %
  Bedouin3388; 65.848; 42.167,707; 64.2
  Jewish1749; 34.2 (p = 0.019)66; 57.9 (p < 0.001)37,714; 35.8
  • * Comparison was made for each of the exposure groups separately comparing with the unexposed group.

  • ** Population group was determined from information in administrative databases. COX: cyclooxygenase.