Table 3.

Baseline Disease Severity Score according to autoantibody status.

System	Percentage of Patients with DSS≥ 1
	Autoantibody Subset^*			p^**
	Scl-70, n = 94	ACA, n = 170	RNAP, n = 23	Scl-70 vs ACA	Scl-70 vs RNAP	ACA vs RNAP
General	16.3	16.6	26.1	> 0.999	0.364	0.255
Peripheral vascular	77.4	58.8	47.8	0.003	0.009	0.372
Skin	92.6	72.4	100	< 0.0001	0.342	0.001
Joint/tendon	54.3	20.1	43.5	< 0.0001	0.363	0.018
Muscle	14.0	6.5	4.3	0.071	0.296	> 0.999
Gastrointestinal tract	34.4	29.2	22.7	0.404	0.325	0.622
Lung	84.9	68.5	69.6	0.0032	0.127	> 0.999
Heart	14.0	8.8	8.7	0.213	0.732	> 0.999
Kidney	5.4	3.5	8.7	0.524	0.626	0.244

↵* Data concern patients whose serum contains only 1 of the 3 autoantibodies.
↵** Fisher’s exact test. P values in bold type are considered statistically significant (p < 0.017; Bonferroni correction). DSS: Disease Severity Score; RNAP: RNA polymerase antibodies; ACA: anticentromere antibodies.