Baseline characteristics of study subjects.
| Normal Renal Function at Baseline | Abnormal Renal Function at Baseline | Scleroderma Renal Crisis | |
|---|---|---|---|
| Complete case analysis (only patients without missing visits; n = 401) | |||
| n (%) | 295 (73.57) | 83 (20.70) | 23 (5.74) |
| Mean age (SD), yrs | 53.37 (10.64) | 64.77 (8.63) | 55.22 (9.69) |
| Female, n (%) | 258 (87.46) | 79 (95.18) | 20 (86.96) |
| Black, n (%) | 4 (1.36) | 0 (0) | 0 (0) |
| Limited disease, n (%) | 181 (61.36) | 58 (69.88) | 9 (39.13) |
| Mean weight, kg (SD) | 71.32 (16.14) | 58.02 (10.76) | 70.93 (20.00) |
| Mean weight change, kg/year (SD) | 0.41 (3.67) | −0.25 (2.78) | −0.56 (3.15) |
| Mean creatinine, μmol/l (SD) | 72.38 (15.91) | 103.01 (50.24) | 177.74 (114.50) |
| Mean creatinine clearance, ml/min | 93.34 (29.57) | 47.54 (9.72) | 46.15 (28.15) |
| Disease duration, yrs (SD) | 9.76 (7.68) | 14.35 (10.96) | 8.40 (6.19) |
| Whole cohort (all available cases: n = 561) | |||
| n (%) | 420 (74.87) | 112 (19.89) | 29 (5.15) |
| Mean age (SD), yrs | 52.84 (11.31) | 65.70 (9.49) | 54.72 (9.24) |
| Female, n (%) | 364 (86.67) | 107 (95.54) | 22 (75.86) |
| Black, n (%) | 5 (1.19) | 1 (0.89) | 0 (0) |
| Limited disease, n (%) | 245 (58.33) | 73 (65.18) | 10 (34.48) |
| Mean weight, kg (SD) | 71.50 (16.21) | 57.88 (11.13) | 69.35 (18.48) |
| Mean weight change, kg/year (SD) | 0.58 (4.26) | −0.10 (2.85) | −0.67 (3.06) |
| Mean creatinine, μmol/l (SD) | 72.04 (15.38) | 110.10 (95.39) | 179.7 (113.50) |
| Mean creatinine clearance, ml/min | 94.78 (28.77) | 46.46 (10.80) | 45.75 (26.57) |
| Disease duration, yrs (SD) | 10.31 (8.22) | 13.96 (10.67) | 8.00 (6.34) |