Non-disease-related differences between patients with normal and abnormal renal function at baseline.
| Patients with Normal Renal Function at Baseline | Patients with Abnormal Renal Function at Baseline | p | |
|---|---|---|---|
| Diabetes mellitus, % | 3.39 | 6.02 | 0.44 |
| Hypertension, % | 22.71 | 43.37 | 0.00 |
| Congestive heart failure, % | 2.37 | 9.64 | 0.01 |
| Overlap with systemic lupus erythematosus, % | 1.36 | 2.41 | 1.00 |
| Nephrotoxic medications | |||
| ACE inhibitors, % | 12.20 | 22.89 | 0.01 |
| Angiotension receptor blockers, % | 8.14 | 13.25 | 0.05 |
| Nonsteroidal antiinflammtory drugs, % | 19.32 | 20.48 | 0.23 |
| D-penicillamine, % | 1.02 | 6.02 | 0.58 |
| Cyclosporine, % | 0.00 | 0.00 | 1.00 |
| Corticosteroids, % | 15.93 | 14.46 | 0.33 |
| Drugs for heart failure, % | 2.03 | 10.84 | 0.01 |
| Anti-arrythmics, % | 1.69 | 7.23 | 0.04 |
| Prostacyclins, % | |||
| Flolan, % | 0.68 | 0.00 | — |
| Trepostinil (UT-15), % | 0.68 | 0.00 | — |
| Iloprost, % | 0.68 | 0.00 | — |
ACE: angiotensin-converting enzyme.