Genotyping and allele frequency of CCR6 single-nucleotide polymorphism in patients with rheumatoid arthritis and in controls. Significant values are shown in bold type.
| p and OR (95% CI) | ||||||
|---|---|---|---|---|---|---|
| Genotype | Cases (%), n = 400 | Controls (%), n = 680 | Genotype, p | Dominant, p | Recessive, p | Allelic, p |
| AA | 83 (21.3) | 107 (16.1) | 0.0081** | 0.0046** | 0.0323* | 0.0020** |
| AG | 197 (50.5) | 315 (47.2) | 1.48 (1.13–1.94) | 1.42 (1.03–1.95) | 1.32 (1.11–1.58) | |
| GG | 110 (28.2) | 245 (36.7) | ||||
| A | 363 (46.5) | 529 (39.7) | ||||
| G | 417 (53.5) | 805 (60.3) | ||||
| Female | ||||||
| AA | 68 (21.3) | 55 (16.5) | 0.0122* | 0.0038** | 0.1173 | 0.0051** |
| AG | 166 (52.0) | 154 (46.3) | 1.63 (1.17–2.28) | 1.37 (0.92–2.03) | 1.37 (1.10–1.70) | |
| GG | 85 (26.7) | 124 (37.2) | ||||
| A | 302 (47.3) | 264 (39.6) | ||||
| G | 336 (52.7) | 402 (60.4) | ||||