Table 1.

Clinical and laboratory characteristics of the patients and controls. All data are mean ± SD unless otherwise indicated.

Characteristics	Patients with RA	Disease Controls	p
Age, yrs	47.37 ± 13.63	45.71 ± 14.93	0.485
Women, n	150	77	0.185
ESR, mm/h	46.17 ± 21.37	42.91 ± 18.35	0.531
CRP, mg/dl	19.52 ± 15.19	17.52 ± 12.33	0.421
RF, U/ml	451.59 ± 99.84	50.27 ± 61.04	0.005^*
ACPA2, U/ml	277.16 ± 192.67	6.85 ± 0.86	< 0.001^*
Anti-Sa, U/ml	54.01 ± 71.69	6.42 ± 8.07	< 0.001^*

↵* P values < 0.05 were considered statistically significant. RA: rheumatoid arthritis; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; RF: rheumatoid factor; ACPA2: anticitrullinated protein antibodies, second generation.