Hazard ratio (HR) for hemodialysis according to treatment status of biologics.
| HR (95% CI) | p | |
|---|---|---|
| Sex- and age-adjusted | 0.34 (0.15, 0.75) | 0.007 |
| Multivariable-adjusted, model 1 | 0.35 (0.09, 1.32) | 0.122 |
| Multivariable-adjusted, model 2 | 0.58 (0.13, 2.47) | 0.46 |
| Subjects with Ccr ≥ 30 ml/min/1.73 m2* | ||
| Sex- and age-adjusted | 0.16 (0.02, 1.32) | 0.088 |
| Multivariable-adjusted, model 1 | 0.42 (0.04, 4.54) | 0.477 |
| Multivariable-adjusted, model 2 | 0.74 (0.06, 8.65) | 0.814 |
Multivariable model adjusted for sex, age, hematocrit (Ht), albumin (Alb), creatinine (Cr), and C-reactive protein (CRP). Numbers of valid cases in the biologic and nonbiologic groups were 52 and 77 for the sex- and age-adjusted model; 35 and 72 for multivariable model 1 adjusted for sex, age, Ht, Alb, Cr, and CRP; and 35 and 65 for multivarable model 2 adjusted for sex, age, Ht, Alb, creatinine clearance (Ccr), and CRP, respectively.
↵* Ccr < 30 ml/min/1.73 m2 was excluded from this analysis. Multivariable model adjusted for sex, age, Ht, Alb, Cr, and CRP. Numbers of valid cases in biologic and nonbiologic groups were 31 and 47 for the sex- and age-adjusted model; 31 and 46 for multivariable model 1 adjusted for sex, age, Ht, Alb, Cr, and CRP; and 31 and 46 for multivariable model 2 adjusted for sex, Ht, Alb, Ccr, and CRP, respectively.