Drinking Status + Smoking Status | Cases/Controls | OR (95% CI) | |||
---|---|---|---|---|---|
Crude | p | Adjusted* | p | ||
Drinking + nonsmoking | 49/249 | 1.0 (reference) | 1.0 (reference) | ||
Drinking + ever-smoking | 45/98 | 2.33 (1.46–3.72) | < 0.0001 | 3.44 (2.03–5.82) | < 0.0001 |
Nondrinking + nonsmoking | 63/132 | 2.43 (1.58–3.72) | < 0.0001 | 2.56 (1.57–4.17) | < 0.0001 |
Nondrinking + ever-smoking | 14/13 | 5.47 (2.42–12.4) | < 0.0001 | 6.98 (2.87–17.0) | < 0.0001 |
Multiplicative interaction measure | 0.97 (0.38–2.47) | 0.944 | 0.79 (0.29–2.18) | 0.653 | |
Additive interaction measure | |||||
Relative excess due to interaction | 1.71 (–2.57–5.99) | 0.433 | 1.98 (–3.90–7.86) | 0.509 | |
Attributable proportion due to interaction | 0.31 (–0.25–0.87) | 0.272 | 0.28 (–0.40–0.91) | 0.796 | |
Synergy index | 1.62 (0.59–4.49) | 0.352 | 1.50 (0.53–4.19) | 0.444 |
↵* Adjusted for age, region, and education background. SLE: systemic lupus erythematosus.