Table 6.

Association between renal biopsy National Institutes of Health (NIH) activity and chronicity indices and clinical renal predictors.

VariableEstimated Effect on Mean Renal Biopsy NIH Activity Index per 1 Unit of Variablep
Urinalysis protein1.366 ± 0.7680.08
Urinalysis red blood cells/hpf0.144 ± 0.0750.06
Urinalysis white blood cells/hpf0.191 ± 0.0560.0006
Urine creatinine level0.016 ± 0.0120.18
Urine protein/creatinine ratio0.238 ± 0.3550.50
24-h protein4.020 ± 0.345< 0.0001
Serum creatinine−0.231 ± 1.6970.47
SLICC renal activity score0.437 ± 0.1560.005
Log-normalized VCAM−1.329 ± 1.1540.25
Log-normalized NGAL−0.878 ± 1.3160.50
Estimated Effect on Mean Renal Biopsy NIH Chronicity Index per 1 Unit of Variablep
Urinalysis protein−0.361 ± 0.3570.31
Urinalysis red blood cells/hpf0.017 ± 0.0380.66
Urinalysis white blood cells/hpf0.009 ± 0.0260.71
Urine creatinine level−0.003 ± 0.0050.60
Urineprotein/creatinine ratio−0.172 ± 0.1570.28
24-h protein−1.043 ± 0.6030.084
Serum creatinine2.511 ± 0.549< 0.0001
SLICC renal activity score−0.036 ± 0.0830.66
Log-normalized VCAM−0.627 ± 0.5180.23
Log-normalized NGAL−0.845 ± 0.5770.14
  • SLICC: Systemic Lupus International Collaborating Clinics; VCAM-1: vascular cell adhesion molecule-1; NGAL: neutrophil gelatinase-associated lipocalin; hpf: high power field.