Table 3.

Association of clinical, laboratory, and radiographic features with late versus adult-onset ankylosing spondylitis. The OR corresponds to a unit-increase in the variable if not addressed.

FeatureOR (95% CI)
Initial symptoms/signs
  Inflammatory back pain0.29 (0.11–0.78)*
  Peripheral arthritis0.96 (0.31–2.97)
  Enthesitis1.46 (0.41–5.27)
  Uveitis2.25 (0.70–7.18)
  Peripheral arthritis/enthesitis only1.57 (0.44–5.63)
OutcomeOR (95% CI)††
  BASDAI0.88 (0.71–1.09)
  BASFI0.89 (0.72–1.11)
  BASMI1.08 (0.78–1.49)
  BASG0.97 (0.82–1.14)
  CRP > 0.5 vs ≤ 0.5 mg/dl0.48 (0.11–2.01)
  ESR > 20 vs ≤ 20 mm/h1.30 (0.29–5.90)
  IgA > 453 vs ≤ 453 mg/dl0.72 (0.09–5.88)
  Sacroiliitis0.87 (0.44–1.73)
  mSASSS cervical spine0.83 (0.63–1.09)
  mSASSS lumbar spine0.85 (0.67–1.08)
  • Adjusted for sex and HLA-B27.

  • †† Adjusted for sex, HLA-B27, and disease duration.

  • * Statistical significance. Definitions as in Table 1.