Mean risks physicians are willing to accept in exchange for various reductions in ambulatory and resting pain. For example, on average, physicians are willing to accept an increase in bleeding ulcer risk of 0.7% (95% CI 0.4%–1.7%) for an improvement in ambulatory pain of 75 mm to 50 mm (severe to moderate). All risks are given in percentages.
| Improvement in Benefit | Bleeding Ulcer Risk (95% CI) | Heart Attack Risk (95% CI) | Stroke Risk (95% CI) |
|---|---|---|---|
| Ambulatory pain | |||
| 75 mm to 50 mm | 0.72 (0.35, 1.65) | 0.76 (0.27, 1.48) | 0.74 (0.26, 1.52) |
| 50 mm to 25 mm | 0.55 (0.06, 1.18) | 0.52 (0.06, 1.57) | 0.49 (0.06, 1.62) |
| 25 mm to 0 mm | 0.66 (0.27, 1.56) | 0.68 (0.22, 1.33) | 0.65 (0.21, 1.36) |
| Resting pain | |||
| 75 mm to 50 mm | 0.17 (0.01, 0.50) | 0.16 (0.01, 0.51) | 0.15 (0.01, 0.48) |
| 50 mm to 25 mm | 0.27 (0.03, 0.58) | 0.26 (0.03, 0.67) | 0.24 (0.03, 0.66) |
| 25 mm to 0 mm | 0.75 (0.50, 1.17) | 0.80 (0.37, 1.51) | 0.78 (0.34, 1.56) |