Association between CENP-A positive and negative status and limited and diffuse skin involvement during followup in patients with limited skin disease at baseline and at least 3 years of followup (n = 209).
| Status | Limited Disease Patients Who Remained Limited Over Followup (%) | Limited Disease Patients Who Became Diffuse Over Followup (%) |
|---|---|---|
| CENP-A positive | 85 (81) | 20 (19) |
| CENP-A negative | 65 (62) | 39 (38) |
CENP: centromeric proteins.