Clinical characteristics of 39 systemic lupus erythematosus (SLE) patients with flare and after resolution of flare. Data are median ± SD unless otherwise indicated.
| Characteristic | SLE with Flare | Resolution of Flare | p |
|---|---|---|---|
| Malar rash, n (%) | 9 (23.1) | 4 (10.3) | 0.224 |
| Serositis, n (%) | 3 (7.7) | 0 (0) | 0.24 |
| Oral ulcer, n (%) | 10 (25.6) | 0 (0) | 0.001 |
| Arthritis, n (%) | 25 (64.1) | 1 (2.6) | < 0.001 |
| Photosensitivity, n (%) | 2 (5.1) | 0 (0) | 0.494 |
| Alopecia, n (%) | 11 (28.2) | 2 (5.1) | 0.013 |
| Renal disease, n (%) | 8 (20.5) | 2 (5.1) | 0.087 |
| Neurologic disorder, n (%) | 1 (2.6) | 0 (0) | 1.0 |
| Anti-dsDNA, IU/ml | 38.82 ± 42.58 | 22.05 ± 30.30 | 0.035 |
| Hemoglobin, g/dl | 11.75 ± 1.57 | 12.34 ± 1.30 | 0.107 |
| Leukocytes, μl | 6375 ± 4271 | 5748 ± 2517 | 0.952 |
| Lymphocytes, μl | 1134 ± 752 | 1305 ± 754 | 0.131 |
| Platelets, × 103/μl | 237.36 ± 85.51 | 256.54 ± 72.05 | 0.322 |
| Complement 3, mg/dl | 60.38 ± 25.23 | 88.57 ± 26.61 | < 0.001 |
| ESR, mm/h | 25.21 ± 20.12 | 15.92 ± 17.22 | 0.017 |
| SLEDAI score | 10.74 ± 5.11 | 2.1 ± 1.83 | < 0.001 |
| CRP, mg/dl | 0.06 (0.03, 0.15) | 0.05 (0.02, 0.13) | 0.333 |
| S100A8/A9, μg/ml | 1.07 (0.49, 3.05) | 0.86 (0.4, 4.01) | 0.78 |
| Procalcitonin, ng/ml | 0 (0, 0) | 0 (0, 0) | 1.0 |
ESR: erythrocyte sedimentation rate; SLEDAI: Systemic Lupus Erythematosus Disease Activity Index; CRP: C-reactive protein. CRP, S100A8/A9, and procalcitonin are expressed as median (interquartile range). Other data are number (%) or mean ± SD.